Patent documents Recovery of rare earth elements and compounds from coal ash Abstract Rare earth elements are recovered from coal ash. The coal ash with rare earth elements can be treated with a mineral acid to form an aqueous mineral acid solution. The aqueous mineral acid solution can be extracted to form an organic solution that includes the rare earth salts. The organic solution can be mixed with water to form an aqueous solution that includes the rare earth salts. The rare earth elements are separated from the aqueous solution. Description CROSS-REFERENCE TO RELATED APPLICATIONS This application claims the benefit of and priority to U.S. provisional paten

Adverse event reporting

Adverse Event Reporting in Clinical Trials: Time to Include Duration as Well as Severity Abstract This editorial discusses flaws in the current system for reporting adverse events. Assessing the efficacy of therapy involves a complex interplay between the risks and benefits within particular patient populations. The concept of patient benefit has been well established. Direct patient benefits are typically assessed with regard to patients living longer, living better, or both. Assessing risks of therapy can be more difficult. To properly assess risks, one must have a clear understanding of risks imposed by the underlying disease and how that risk might be counterbalanced by therapeutic inter

What is a Serious Adverse Event?

An adverse event is any undesirable experience associated with the use of a medical product in a patient. The event is serious and should be reported to FDA when the patient outcome is: Death Report if you suspect that the death was an outcome of the adverse event, and include the date if known. Life-threatening Report if suspected that the patient was at substantial risk of dying at the time of the adverse event, or use or continued use of the device or other medical product might have resulted in the death of the patient. Hospitalization (initial or prolonged) Report if admission to the hospital or prolongation of hospitalization was a result of the adverse event. Emergency room visits tha

Phases of clinical trials

Phases of clinical research The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment. In the case of pharmaceutical study, the phases start with drug design and drug discovery then proceed on to animal testing. If this is successful, they begin the clinical phase of development by testing for safety in a few human subjects and expand to test in many study participants to determine if the treatment is effective. Phases of clinical trials This page is about the different phases of clinical t

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